Brain function and cerebral blood flow are reduced in me/cfs patients, even at rest, according to a recent brain imaging study.
In a study of 19 ME/CFS and 17 healthy controls, researchers used resting state fMRI to evaluate the functional connectivity of patients at rest.
The study identified decreased intrinsic connectivity among regions within the left fronto-parietal networks.
Also, the study confirmed functional connectivity in patients with ME/CFS was significantly correlated with the severity of their chronic fatigue.
Both the findings of impairment at rest and correlation with fatigue severity add to mounting evidence of physical dysfunction in ME/CFS and highlight areas for future research into the disabling disease.
About Resting State fMRI
Resting state fMRI (rsfMRI or R-fMRI) is a method of functional brain imaging that can be used to evaluate regional interactions that occur when a subject is not performing an explicit task. The resting state approach is useful to explore the brain’s functional organization and to examine if it is altered in neurological or psychiatric diseases.
Resting-state functional connectivity research has revealed a number of networks which are consistently found in healthy subjects, different stages of consciousness and across species, and represent specific patterns of synchronous activity.
Tap the toggle below to see the Abstract of the study.
IMAGE (CROPPED): by Polygon Medical Animation